Which of the following is a non-NRT smoking cessation medication?

• A. Varenicline
• B. NRT
• C. Nicoderm
• D. Nicotine Gum

Answer: (A)

Non-nicotine approaches to help quit are medicines that don’t supply nicotine. This medication fits that description because it does not provide nicotine at all. Instead, it works by binding to the same nicotinic receptors in the brain but only partially activates them, which helps ease withdrawal and cravings while also blocking nicotine’s rewarding effects if someone smokes while taking it. That dual action supports abstinence without delivering nicotine.

In contrast, the other choices deliver nicotine through patches or gum, which are classic nicotine replacement therapies designed to raise nicotine levels gradually to blunt withdrawal. So they are not non-NRT options.